For nearly 50 years, Purdue has been a global leader in engineering applied to medicine, providing significant advances in cardiac care, orthopedic implants, medical imaging systems, drug delivery, and tissue engineering. Today, the Purdue College of Engineering is expanding its research enterprise in numerous emerging areas such as molecular imaging, electroceuticals, wearable devices, and machine learning for connected healthcare.

With more than $350 million in external grants and awards for medical research from federal, state and private sources, Indiana University School of Medicine oversees a comprehensive research enterprise that's nationally recognized for its successes in many specialty areas, including cancer, genomic medicine, diabetes, Alzheimer's disease, transplantation, alcoholism, bone and stem cell biology, and health outcomes research.

Currently, the two institutions are collaborating on more than 50 research projects ranging from basic to applied in a wide range of clinical specialties and in various stages of research and development, clinical trials, and clinical practice. The following list of collaborative projects is growing in number and scope.

Brain Health and Function

  • AD Study in Human Brains
    Purdue Faculty: Fang Huang
    IU School of Medicine Faculty: Ruben Vidal/Bernardino Ghetti
  • Multimodal hyperspectral imaging of brain activity and connectivity
    Purdue Faculty: Zhongming Liu
    IU School of Medicine Faculty: Robert Worth, Kristine Mosier, Nicholas Barbaro, Thomas Witt, Dragos Sabau, Vicenta Salanova
  • Relating feedforward and feedback network interactions to multimodal imaging
    Purdue Faculty: Zhongming Liu
    IU School of Medicine Faculty: Nicholas Barbaro, Robert Worth
  • Brain imaging for Alzheimer's disease
    Purdue Faculty: Zhongming Liu
    IU School of Medicine Faculty: Andrew Saykin
  • Mapping stomach autonomic circuitry and function for neuromodulation of gastric disorders
    Purdue Faculty: Zhongming Liu
    IU School of Medicine Faculty: Thomas Nowak, John Wo
  • Cortical Excitation/inhibition in epilepsy
    Purdue Faculty: Zhongming Liu
    IU School of Medicine Faculty: Nicholas Barbaro
  • Effects of Gastric Electrical Stimulation on Vagal Afferent Fiber Activation and Symptom Management in Gastroparesis
    Purdue Faculty: Matthew Ward
    IU School of Medicine Faculty: Thomas Nowak, MD
  • High-resolution Ultrastructural Analysis of the Human Abdominal and Thoracic Vagal Trunk via Transmission Electron Microscopy
    Purdue Faculty: Matthew Ward, Terry Powley
    IU School of Medicine Faculty: John Nowak, Chandreshekhar Kubal, Plamen Mihaylov

Diabetes and Cardiovascular Disease

  • Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact (Microscopy image analysis)
    Purdue Faculty: Edward Delp
    IU School of Medicine Faculty: Kenneth W. Dunn, Bruce Molitoris
  • Aortic valve calcification and stenosis in a mouse model of cardiac fibrosis
    Purdue Faculty: Craig Goergen
    IU School of Medicine Faculty: Jingwu Xie
  • Maymester course: Cardiothoracic Surgery Immersion at IU Methodist Hospital
    Purdue Faculty: Craig Goergen
    IU School of Medicine Faculty: I-Wen Wang
  • Bioengineering Training for Diabetes Research
    Purdue Faculty: Craig Goergen
    IU School of Medicine Faculty: Johnathan D. Tune, Raghu Mirmira
  • Prediction technologies of circulatory shock in emergency department settings
    Purdue Faculty: Young Kim
    IU School of Medicine Faculty: Jeffrey A. Kline
  • Measurement of glucose concentration in exhaled breath condensate
    Purdue Faculty: Jacqueline Linnes
    IU School of Medicine Faculty: Kieren Mather
  • Long-term delivery of modified insulin
    Purdue Faculty: Kinam Park
    IU School of Medicine Faculty: Michael Weiss

Infectious Disease

  • Portable Platform for Malaria Detection
    Purdue Faculty: Tamara Kinzer-Ursem, Jacqueline Linnes
    IU School of Medicine Faculty: Chandy John
  • Smartphone-based diagnostic for HIV-self testing
    Purdue Faculty: Jacqueline Linnes, Tamara Kinzer-Ursem, Steven Wereley
    IU School of Medicine Faculty: Christopher Emery

Cancer and Developmental Disorders

  • Intratumoral Chemo Radio Combination Therapy for Locally Advanced/Metastatic Solid Tumors
    Purdue Faculty: You-Yeon Won
    IU School of Medicine Faculty: Mark P. Langer, Gregory A. Durm
  • Walther Cancer Foundation Oncology Physical Sciences & Engineering Research Embedding Program
    Purdue Faculty: Marietta Harrison
    IU School of Medicine Faculty: Chandru Sundaram
  • Automated Supine Pressor Test Device for Prediction of Preeclampsia
    Purdue Faculty: Craig Goergen
    IU School of Medicine Faculty: David Haas
  • Breast cancer drug resistance
    Purdue Faculty: Bumsoo Han
    IU School of Medicine Faculty: J-T Zhang
  • Discovery of Ref-1 inhibitors
    Purdue Faculty: Bumsoo Han
    IU School of Medicine Faculty: Mark Kelley
  • Pancreatic cancer treatments, Discovery of Ref-1 inhibitors
    Purdue Faculty: Bumsoo Han
    IU School of Medicine Faculty: Melissa Fishel
  • Breast filler following lumpectomy
    Purdue Faculty: Sherry Harbin
    IU School of Medicine Faculty: Carla Fisher
  • Novel biophotometric imaging method for assessing early dermal changes leading to skin cancer
    Purdue Faculty: Young Kim
    IU School of Medicine Faculty: Raymond L. Konger
  • Clinical validation of noninvasive hemoglobin monitoring tools/prediction methods for anemia
    Purdue Faculty: Young Kim
    IU School of Medicine Faculty: Attaya Suvannasankha
  • Tumor microenvironment on chips
    Purdue Faculty: Kinam Park, Bumsoo Han, Stephen F. Konieczny
    IU School of Medicine Faculty: Murray Korc
  • Fabrication and evaluation of soft contact lens-based electronics
    Purdue Faculty: Chi Hwan Lee
    IU School of Medicine Faculty: Shaohui Liu
  • Electronic soft contact lenses for continuous, spatially-resolved mapping of ocular functions
    Purdue Faculty: Chi Hwan Lee
    IU School of Medicine Faculty: Pete Kollbaum, Arthur Bradley, Neil Pence and S. P. Srinivas
  • Infant warming sensors during kangaroo mother care
    Purdue Faculty: Jacqueline Linnes
    IU School of Medicine Faculty: Sherri Bucher

Musculoskeletal Health

  • Mechanical Size Effects and Bone Failure
    Purdue Faculty: Thomas Siegmund
    IU School of Medicine Faculty: M.R. Allen
    Purdue School of Engineering and Technology, Indianapolis Faculty: J. Wallace
  • Understanding the role of osteocyte estrogen receptor beta on bone remodeling and mechanobiology
    Purdue Faculty: Russ Main
    IU School of Medicine Faculty: Teresita Bellido
  • Development of a 3D bone tissue culture system
    Purdue Faculty: Russ Main
    IU School of Medicine Faculty: Teresita Bellido, Fredrick Pavalko

Education and Training

  • Objective workload metrics for enhancing surgical training and performance
    Purdue Faculty: Denny Yu, Juan Wachs
    IU School of Medicine Faculty: Chandru Sundaram
  • Fostering Skill Building for Surgeons
    Purdue Faculty: Denny Yu
    IU School of Medicine Faculty: Dimitrios Stefanidis
  • AHRQ: GestureClean: A Touchless Interaction Language for the Operating Room
    Purdue Faculty: Juan P Wachs, Lingsong Zhang
    IU School of Medicine Faculty: Richard (Ben) Rodgers
  • AHRQ: See-what-I-do: Increasing mentor and trainee sense of co-presence in trauma surgeries with the STAR platform
    Purdue Faculty: Juan P Wachs, Voicu Popescu
    IU School of Medicine Faculty: Ben Zarzaur, Brian Mullis, Sherri Marley
  • Transforming training and augmenting performance with realtime cognitive workload sensing
    Purdue Faculty: Juan P Wachs, Denny Yu
    IU School of Medicine Faculty: Chandru Sundaram

Learn more:

Anantha Shekhar, MD, PhD
Whether we are developing new tests to diagnose cancer at earlier stages, improving surgical devices, or seeking ways to regrow damaged organs, we need the best minds from many disciplines working together for the benefit of patients. We are fortunate to have such strong programs in medicine and engineering in Indiana, and we feel confident that our joint efforts will strengthen the state's critical life sciences sector.
Anantha Shekhar, MD, PhD
- Director, Executive Associate Dean for Research Affairs, Indiana University School of Medicine and Director of the Indiana Clinical and Translational Sciences Institute